This study examines the various stages in the DENV infection process to better understand the mechanism of Wolbachia-mediated virus blocking (WMVB). The results suggest that infection with Wolbachia does not inhibit DENV binding or cell entry‚ but reduces virus replication. In contrast to a previous report‚ researchers observed a similar reduction in replication of West Nile virus (WNV). This reduced replication is associated with rapid viral RNA degradation in the cytoplasm.
Want to learn more about the World Mosquito Program and our sustainable and nature-based Wolbachia method?
Be part of our journey to protect the lives of millions of people.
Subscribe to our newsletter to up to date with global progress in the fight against mosquito-borne disesases.