The AWED trial (Applying Wolbachia to Eliminate Dengue) to assess the efficacy of Wolbachia-infected mosquito deployments to reduce dengue incidence in Yogyakarta‚ Indonesia: study protocol for a cluster randomised controlled trial | World Mosquito Program Skip to main content
This study protocol describes the first trial to measure the efficacy of Wolbachia in reducing dengue virus transmission in the field. The study is a parallel‚ two-arm‚ non-blinded cluster randomised controlled trial conducted in a single site in Yogyakarta‚ Indonesia. The aim is to determine whether large-scale deployment of Wolbachia-infected Ae. aegypti mosquitoes leads to a measurable reduction in dengue incidence in treated versus untreated areas.