We have growing evidence for the effectiveness and safety of our Wolbachia method and have set up projects in 11 countries.
We have released Wolbachia-carrying mosquitoes to reach approximately 5 million people (as at December 2019). In areas where Wolbachia is self-sustaining at a high level, there has been a significant reduction in the number of dengue cases.
Results from our project sites show dengue incidence is significantly lower in Wolbachia-treated communities compared with untreated neighboring populations. Our most recent gold-standard trial in Yogyakarta showed a 77% reduction in dengue incidence in Wolbachia treated areas compared with untreated areas.
Safe and self-sustaining
Wolbachia is safe and its virus-blocking properties persist in mosquito populations many years after release.
Reduced disease burden
There have been large reductions in dengue incidence in communities where the World Mosquito Program's method has been applied.
Deployable at large scale
City-wide deployments are in progress in Medellín and Bello, Colombia and Rio de Janeiro and Niterói, Brazil (due to complete in 2019).
Economic benefits forecast
The World Mosquito Program's method is predicted to be cost-saving in urban communities.
Clinical trials underway
Results from a randomised controlled trial in Yogyakarta, Indonesia have recently been announced. Ongoing city-wide trials in Colombia and Brazil hope to release results in 2021.
Independent experts predict that the World Mosquito Program's method will eliminate dengue transmissions for decades.
This graph shows reduced dengue incidence in the project sites where we have finished releasing Wolbachia-carrying mosquitoes.
Data to March 2020
|Country & Sites||Release status||Area||People reached||Impact-to-date|
|Releases completed 2018||2.2 km²||15,670||Dengue incidence ↓ 79% compared to neighbouring Nha Trang city.|
|Releases completed 2017||18.4 km²||242,665||Results of gold-standard RCT show dengue incidence ↓ 77%. Parallel quasi-experimental trial showed ↓ 79%.|
|Releases completed 2011–2019||300 km²||312,183||Dengue incidence ↓ 96%. Effective elimination of dengue as a public health problem.|
ColombiaMedellin and Bello
|Releases ongoing as of June 2019||131.01 km²||2,760,152||No dengue outbreaks in Wolbachia-treated areas of city-wide deployments.|
BrazilRio de Janeiro and Niteroi
|Releases ongoing as of June 2019||129 km²||1,264,890||Preliminary results of city-wide deployments indicate dengue incidence ↓42–74% and chikungunya incidence ↓up to 64%.|
Western PacificSuva, Nadi, Lautoka Fiji; Port Vila, Vanuatu; South Tarawa, Kiribati
|Releases completed at all Pacific sites as of June 2019||157 km²||351,000||Monitoring ongoing, with results expected 2020.|
United Nations’ Sustainable Development Goals
In 2015, world leaders agreed to 17 Global Goals for Sustainable Development, to create a better world by 2030.
Our work supports many of the Sustainable Development Goals (SDGs), primarily SDG #3: Good health and well-being, in particular Target 3.3: Fight communicable diseases. This target calls for the end to epidemics of AIDS, tuberculosis, malaria and neglected tropical diseases and to combat hepatitis, water-borne diseases and other communicable diseases. Dengue, Zika and chikungunya are classified as neglected tropical diseases.
Our work also supports
Costly medical treatment for mosquito-borne diseases cause financial hardship for individuals and households, and time spent recuperating restricts their ability to earn a living or pursue education. Our work towards reducing these diseases will help to decrease poverty and increase economic prosperity.
The global effort to control and eliminate mosquito-borne diseases is one of the largest public health initiatives ever undertaken. Our work towards mobilising financial resources from partners and funders, and working in partnership with government, non-government organisations and local communities, is helping to reduce mosquito-borne diseases.
Women and girls are particularly affected by mosquito-borne diseases such as dengue and Zika.
Our research shows that girls with dengue are at higher risk of severe symptoms and death than boys.
Women who are infected by Zika virus during pregnancy can bear children with serious health conditions, including microcephaly and Guillain-Barré syndrome, which can cause life-long disability.
The World Mosquito Program’s innovative method to prevent mosquito-borne diseases is, therefore, supporting women and girls to live healthier lives and prevent the risks associated with mosquito-borne diseases.